Section: Module 7: Pharmacological Interventions for Tobacco Dependence Treatment | Prevention and Treatment of Tobacco Use

Module 7: Lesson 1: Smoking Cessation Drugs: Modes of Action and Classifications

Student Learning Outcomes:

Upon completion of this lesson, you will be able to:

Describe the mechanisms of action of various smoking cessation drugs.
Explain how these mechanisms contribute to smoking cessation.
Categorize drugs as first-line or second-line drugs.
Discuss the factors that determine these classifications and their implications for prescribing.

Approximate time required to complete the readings (at 144 words/minute) and assignments for this module: 1 hour and 50 minutes.

Required Learning Resources and Activities

Smoking Cessation Medications URL

Read the page. (5 minutes)

National Library of Medicine - 2023

Pharmacotherapy for Smoking Cessation in Adults URL

Read entire page. (35 minutes)

Indian Journal of Psychiatry - 2014

Pharmacologic Agents for Smoking Cessation: A Clinical Review URL

Read the abstract, introduction/background, discussion, and conclusion. (45 minutes)

Clinical Pharmacology - 2010

The Current State of Tobacco Cessation Treatment URL

Read full document. (25 minutes)

Ethiopian Journal of Health Sciences - 2018

Module 7: Lesson 2: Correct Use and Side Effects of Smoking Cessation Medications

Student Learning Outcomes:

Upon completion of this lesson, you will be able to:

Describe the correct usage of various smoking cessation medications.
Discuss the importance of medication adherence and strategies to promote it.
Identify potential side effects and contraindications of various smoking cessation medications.
Discuss the importance of monitoring for adverse events during treatment.
Explain how to adapt pharmacotherapy to individual patient needs, taking into account potential exclusions.

Approximate time required to complete the readings (at 144 words/minute) and assignments for this module: 2 hours and 45 minutes.

Required Learning Resources and Activities

Stop Smoking Treatments URL

Read the page. (5 minutes)

NHS - 2022

Interventions to Increase Adherence to Medications for Tobacco Dependence URL

Read the abstract, introduction/background, discussion, and conclusion. (30 minutes)

Cochrane Database Systems Review - 2019

How do Smoking Cessation Aids Work? URL

Read the page. (10 minutes)

Rx List - 2023

Pharmacotherapy for Smoking Cessation in Adults URL

Read the entire article. (75 minutes)

UpToDate - 2023

Multiple Pharmacotherapy Adaptations for Smoking Cessation Based on Treatment Response in Black Adults Who Smoke URL

Read the abstract, introduction/background, discussion, and conclusion. (35 minutes)

JAMA Network Open - 2023

Quiz: Module 7

To access the quiz, click on the name of the quiz provided above. On the following screen, click the attempt quiz button to view the case studies and respond to the questions.

TO PASS THIS QUIZ YOU MUST OBTAIN A SCORE OF 80%.

Introduction

Course Registration

Peer Corner

Pre-Test

Module 1: Introduction to Tobacco Consumption as a Public Health Problem

History of Tobacco

A Social and Cultural History of Smoking

The History of the Discovery of the Cigarette–lung Cancer Link: Evidentiary Traditions, Corporate Denial, Global Toll

Types of Tobacco Products

Anatomy of a Cigarette

Tobacco Smoke and Involuntary Smoking: Composition, Exposure and Regulations

Evolution of the Global Smoking Epidemic Over the Past Half-century: Strengthening the Evidence Base for Policy Action

The Global Burden of Tobacco

Factors that Influence Tobacco Use

Risk Factors

Tobacco: Preventing Uptake, Promoting Guitting and Treating Dependence

National, Regional, and Global Prevalence of Cigarette Smoking Among Women/females in the General Population: a Systematic Review and Meta-analysis

Achieving Health Equity in Tobacco Control

Factors That Influence Tobacco Use Among Four Racial/Ethnic Minority Groups

Intergenerational differences in smoking among West Indian, Haitian, Latin American, and African blacks in the United States

Quiz: Module 1

Risk and Protective Factors for Vaping and Smoking Among High School Students in Maine

Patterns of Smoking Cessation Among U.S. Adults, Young Adults, and Youth

Smoking Cessation, Quit Attempts and Predictive Factors among Vietnamese Adults in 2020

Explanations of Socio-economic Disparities in Smoking

Tobacco and Socioeconomic Status

Module 2: Health, Social, Economic, and Environmental Impact of Tobacco Use and Exposure

Health Problems Caused by Secondhand Smoke

The Health Consequences of Smoking —50 Years of Progress A Report of the Surgeon General

Women and Smoking: The Effect of Gender on the Epidemiology, Health Effects, and Cessation of Smoking

Pathogenesis of (smoking-related) Non-communicable Diseases—Evidence for a Common Underlying Pathophysiological Pattern

A Biopsychosocial Approach to Examining Tobacco-related Health Disparities Among Racially Classified Social Groups

Respiratory Diseases

Secondhand and Thirdhand Smoke: A Review on Chemical Contents, Exposure Routes, and Protective Strategies

WHO Global Report on Trends in Prevalence of Tobacco Use 2000–2025 Fourth Edition

Economic Costs of Tobacco Use

Smoking-Attributable Morbidity, Mortality, and Economic Costs

Global Economic Cost of Smoking-attributable Diseases

Tobacco and the Environment

Plastics, the Environment and the Tobacco Industry

Tobacco and Non-Communicable Diseases

Six Cost-Effective Actions Endorsed by WHO to Reduce Tobacco’s Deadly Toll

Quiz: Module 2

Module 3: Understanding the Neurobiology and Pathophysiology of Nicotine Addiction & Withdrawal

Nicotine Addiction: Neurobiology and Mechanism

Nicotine Pharmacology

Neurobiological and Neurophysiological Mechanisms Underlying Nicotine Seeking and Smoking Relapse

Nicotine Addiction: Neurobiology and Mechanism

Neurogenetic Determinants and Mechanisms of Addiction to Nicotine and Smoked Tobacco

Influence of Processes of Change on Stages of Change for Smoking Cessation

What is Nicotine Withdrawal?

New Mechanisms and Perspectives in Nicotine Withdrawal

Discussion Forum 1

Quiz: Module 3

Neural Mechanisms Underlying Nicotine Addiction: Acute Positive Reinforcement and Withdrawal

Module 4: Tobacco Cessation as a Process

Guidelines for implementation of Article 14 WHO Framework Convention on Tobacco Control

Improving Smoking Cessation Approaches at the Individual Level

Influence of Processes of Change on Stages of Change for Smoking Cessation

Promotion of Smoking Cessation Using the Transtheoretical Model: Short-Term and Long-Term Effectiveness for Workers in Coastal Central Taiwan

How Smokers go About Quitting

Reasons to Quit and Barriers to Quitting Smoking in US Young Adults

The Views and Experiences of Smokers Who Quit Smoking Unassisted. A Systematic Review of the Qualitative Evidence

Discussion Forum 2

Quiz: Module 4

Barriers and Facilitators for Smoking Cessation in Chronic Smokers with Atherosclerotic Cardiovascular Disease Enrolled in a Randomized Intervention Trial: A Qualitative Study

Module 5: Clinical Approach to Smoking Cessation and Tobacco Dependence Treatment

DSM Criteria for Tobacco Use Disorder and Tobacco Withdrawal: A Critique and Proposed Revisions for DSM-5

Smoking Cessation, Version 3.2022, NCCN Clinical Practice Guidelines in Oncology

Adherence to Pharmacological Smoking Cessation Interventions: A Literature Review and Synthesis of Correlates and Barriers

The Impact of Smoking Cessation Attempts on Stress Levels

Smoking Cessation and Weight Gain: A Common Challenge and a Unique Opportunity

The Association of Peer Smoking Behavior and Social Support with Quit Success in Employees Who Participated in a Smoking Cessation Intervention at the Workplace

Household Composition, Smoking Cessation and Relapse: Results from a Prospective Longitudinal Australian Cohort.

Non-cigarette Tobacco Products and POS Policies

Novel Tobacco and Nicotine Products and Their Effects on Health

Providers’ Non-Cigarette Tobacco Use Intervention Practices in Relation to Beliefs about Patients, Prioritization of and Skills for Intervention, and Referral Knowledge in Texas Healthcare Centers Providing Care to Persons with Behavioral Health Needs

Discussion Forum 3: Treatment Program Design: Weight Management and Stress Reduction During Tobacco Cessation

Quiz: Module 5

Weight Gain After Smoking Cessation and Risk of Major Chronic Diseases and Mortality

Integrating Complementary & Alternative Therapies with Conventional Care