This resource refers to brief advice for smoking cessation, however, brief interventions are done in a very similar fashion for all other psychoactive substances. Beginning at the section titled 'Address the topic of smoking and tobacco use' (on page 23 of the page navigator), read to the end of Part 1 (pp. 23 - 33). Pay special attention to the tips and flowcharts that are used in clinical practice, as seen in Tables 7 - 11 and Figure 2. Read Appendices 3 and 4 (pp. 46 - 57) to help you understand how to give cessation advice as per best practices. The rest of this manual is supplementary.