In this activity, you will discuss the issue of the indispensable use of statistics, despite it being an imperfect science and measure. 

Step 1. Review

Review the learning resources for this lesson before answering the question.

Step 2. Analyze

Analyze and discuss the question below.

Step 3. Respond

Respond to the case problem by writing a 300-500-word discussion post with the following inclusions.

Step 4. Share

To share your work, click on the “Add a new discussion topic” button under this post and paste your work in the “Message” box. Make sure to reference others’ intellectual property when necessary. All references should follow 7th Edition APA formatting. For further instructions, see the resource on the Himmelfarb Health Sciences Library: APA citation resource (N.B. references are excluded from word counts).

OPTIONAL Step 5: Interact (10 minutes)

If you would like to, you can reply to your peers' posts in a respectful and professional manner. Ensure that your post engages your peers' ideas by including a reflection on their comments, sharing ideas of other potential difficulties and parties involved, or asking thought-provoking questions. If a peer comments on your posting, please reply. To post a reply, click “Reply” on a particular discussion, write your feedback and then click on “Post to forum.”

Student Learning outcome (Module 1 Lesson 4): Discuss the importance of and identify instances of Random Selection and Random Assignment in Research. 

Step 1. Review

Review the learning resources for this lesson before studying the case problem.

Step 2. Analyze

Analyze the case problem below.

A new drug is introduced. How should an experiment be designed to test its effectiveness? The primary method is comparison. The drug is given to subjects in a treatment group, but other subjects are used as controls ‒ they aren’t treated. The treatment and control groups should be as similar as possible ‒ except for the treatment. Then the responses of the two groups are compared. Subjects should be assigned to the groups at random. A randomized controlled assignment is when an impartial chance procedure is used to assign the subjects to treatment or control. This method provides the best assurance of validity and reliability. However, randomized controlled experiments are hard to do. As a result, doctors often use other designs which are not as good. For example, a new treatment can be tried out on one group of patients, who are compared to “historical controls:” patients treated the old way in the past. Usually, using historical controls, assignment to the groups is not randomized, resulting in a poorly-designed experiment. The problem is that the treatment and historical groups may differ in important ways besides the treatment.

Coronary bypass surgery is a widely used ‒ and very expensive ‒ operation for coronary artery disease. Chalmers and associates identified 29 trials of this surgery (first line of the table below). There were 8 randomized controlled trials, and 7 were quite pessimistic about the value of the operation. By comparison, there were 21 trials with historical controls, and 16 were positive. Three other therapies were evaluated: 5-FU, used in chemotherapy for colon cancer; BCG, used to treat melanoma; and DES, used to prevent miscarriage. The data are given below.

Table 1: A study of studies. Four therapies were evaluated by randomized controlled trials and by trials using historical controls. Conclusions of trials are summarized as positive about the value of the therapy (+) or negative (-).

Why are the randomized controlled studies less enthusiastic, and the less well-designed studies more enthusiastic about the value of the surgery? 

Look at it in view of the data in the table below.

Table 2: Randomized controlled experiments vs. studies with historical controls: three-year survival rates for surgery patients and patients used as controls in trials of coronary bypass surgery.

Step 3. Respond

Respond to the case problem by answering the question: Why are the randomized controlled studies less enthusiastic and the less well-designed studies more enthusiastic about the value of the surgery? 

Step 4. Share

To share your work, access to the first post below and click on the “Reply” button under this post and paste your work into the “Message” box. Make sure to reference others’ intellectual property when necessary. All references should follow 7th Edition APA formatting. For further instructions, see the resource on the Himmelfarb Health Sciences Library: APA citation resource (N.B. references are excluded from word counts).

OPTIONAL Step 5: Interact (10 minutes)

If you would like to, you can reply to your peers' posts in a respectful and professional manner. Ensure that your post engages your peers' ideas by including a reflection on their comments, sharing ideas of other potential difficulties and parties involved, or asking thought-provoking questions. If a peer comments on your posting, please reply. To post a reply, click “Reply” on a particular discussion, write your feedback and then click on “Post to forum.”

In this activity, you will discuss the interpretation of statistical graphs and the relationship between variables. 

Step 1. Review

Review the learning resources for this lesson before answering the question.

Step 2. Analyze

Analyze and discuss the question below.

Step 3. Respond

Respond to the case problem by writing a 300-500-word discussion post with the following inclusions.

Step 4. Share

To share your work, click on the “Add a new discussion topic” button under this post and paste your work in the “Message” box. Make sure to reference others’ intellectual property when necessary. All references should follow 7th Edition APA formatting. For further instructions, see the resource on the Himmelfarb Health Sciences Library: APA citation resource (N.B. references are excluded from word counts).

OPTIONAL Step 5: Interact (10 minutes)

If you would like to, you can reply to your peers' posts in a respectful and professional manner. Ensure that your post engages your peers' ideas by including a reflection on their comments, sharing ideas of other potential difficulties and parties involved, or asking thought-provoking questions. If a peer comments on your posting, please reply. To post a reply, click “Reply” on a particular discussion, write your feedback and then click on “Post to forum.”

Student Learning outcome: Use the Five-Number Summary to Create a Boxplot to Describe a Data Set
In this activity, you will investigate the relationship between boxplot shapes and the corresponding five-number summary.

Step 1. Review

Review the learning resources for this lesson before studying the case problem.

Step 2. Analyze

Analyze the case problem below.

The accompanying figure shows four boxplots labeled A to D. Also given are four five-number summaries, labeled I to IV. Match each five-number summary to the appropriate boxplot. Note that scales are not included on the boxplots, so you will have to consider what the five-number summary implies about the characteristics of the boxplot.

Step 3. Respond

Respond to the case problem by showing the boxplot properties, logic steps, and reasoning you used to match each figure with its corresponding five-number summary.

Step 4. Share

To share your work, access to the first post below and click on the “Reply” button under this post and paste your work into the “Message” box. Make sure to reference others’ intellectual property when necessary. All references should follow 7th Edition APA formatting. For further instructions, see the resource on the Himmelfarb Health Sciences Library: APA citation resource (N.B. references are excluded from word counts).

OPTIONAL Step 5: Interact (10 minutes)

If you would like to, you can reply to your peers' posts in a respectful and professional manner. Ensure that your post engages your peers' ideas by including a reflection on their comments, sharing ideas of other potential difficulties and parties involved, or asking thought-provoking questions. If a peer comments on your posting, please reply. To post a reply, click “Reply” on a particular discussion, write your feedback and then click on “Post to forum.”

In this activity, you will discuss factors of data collection that affect the shape, particularly the skewness, of the data distribution. 

Step 1. Review

Review the learning resources for this lesson before answering the question.

Step 2. Analyze

Analyze and discuss the question below.

Respond to the case problem by writing a 300-500-word discussion post with the following inclusions.

Step 4. Share

To share your work, click on the “Add a new discussion topic” button under this post and paste your work into the “Message” box. Make sure to reference others’ intellectual property when necessary. All references should follow 7th Edition APA formatting. For further instructions, see the resource on the Himmelfarb Health Sciences Library: APA citation resource (N.B. references are excluded from word counts).

OPTIONAL Step 5: Interact (10 minutes)

If you would like to, you can reply to your peers' posts in a respectful and professional manner. Ensure that your post engages your peers' ideas by including a reflection on their comments, sharing ideas of other potential difficulties and parties involved, or asking thought-provoking questions. If a peer comments on your posting, please reply. To post a reply, click “Reply” on a particular discussion, write your feedback and then click on “Post to forum.”