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Blog
Organic Chemistry 2
HPLC - Normal Phase vs Reverse Phase HPLC - Animated
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(4 minutes)
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https://www.youtube.com/watch?v=MLoitPJQH3g
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◄ Separation techniques: Chromatography
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Peer Corner
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'Carboxylic Acids'
Acidity of Carboxylic Acids
'Carboxylic Acid Derivatives'
Chemistry of Amines
Reactions of Amines (continued)
The Leuckart Reaction
Carbonyl Condensations - The Aldol Reaction
Decarboxylation
The Claisen Condensation Reaction
Conjugate Addition and Elimination
Carboxylation
Synthesis, Derivatives, and Reactions of Carboxylic Acids (1 hour)
Quiz: Module 1
Nomenclature of Aldehydes and Ketones
Properties of Aldehydes and Ketones
Oxidation of Alcohols
Alkylation and Acylation of Aromatic Rings - The Friedel-Crafts Reaction
Dihydroxylation of Alkenes
Ozonolysis of Alkenes and Alkynes
Formation of hydrates, hemiacetals, acetals
Reaction with Primary Amines to form Imines
Cyanohydrin Formation
Addition of Hydrides to Aldehydes and Ketones
The Reduction of Aldehydes and Ketones
Oxidation of Aldehydes
Synthesis, Properties, and Reactions of Aldehydes and Ketones (1 hour)
Quiz: Module 2
Acidity of a-Hydrogens
Steric Hindrance
Acidity of Aldehydes and Ketones: Enolate Ions
Nucleophilic Addition Reactions of Enolate Anions
Keto-Enol Tautomerism
Alpha-carbon Reactions
α-Carbon Reactions in the Synthesis Lab - Kinetic vs. Thermodynamic Alkylation Products
Alpha Halogenation of Carbonyls
Enolate alkylation
Introduction - Stereoselectivity
Diastereoselective
The aldol reaction
Quiz: Module 3
Benzene and Aromaticity
Nomencalture of Aromatic Compounds
Bond Strength and Bond Length
The Bonding in Benzene
Benzene’s Unusual Stability
Aromaticity and the Hückel 4n + 2 Rule
Aromatic Substitution Reactions
Aromatic Substitution Reactions Part II
Reactions of Substituent Groups
Reactions of Fused Benzene Rings
Nucleophilic Substitution, Elimination & Addition Reactions of Benzene Derivatives
Nomenclature and Reactions of Aromatic Compounds (1 hour)
Quiz: Module 4
Structure and Properties of Amino Acids
Peptide Bond Formation
Structure of Amides
Proteins and Their Functions- An Overview
Zwitterion
Proteins
'Amino Acids'
Amino Acid Structure
Amino Acids, the Henderson-Hasselbalch Equation, and Isoelectric Points
Organo-phosphorus Compounds
The Characteristics of Nitrogen and Phosphorus-Containing Compounds (1 hour)
Quiz: Module 5
Electromagnetic Radiation
¹H NMR Spectra and Interpretation (Part I)
¹H NMR Spectra and Interpretation (Part II)
¹³C NMR Spectroscopy
Magnetic Properties of Nuclei. Nuclear Spin
Relaxation
The Power of the Fourier Transform for Spectroscopists
The Basis for Differences in Chemical Shift
Infrared (IR) Spectroscopy
IR-Active and IR-Inactive Vibrations
Ultraviolet and visible spectroscopy
Mass Spectrometry
Quiz: Module 6
Pure Substances and Mixtures
Methods for Separating Mixtures
Step-by-Step Procedures For Extractions
'Distillation'
Separation techniques: Chromatography
Techniques of Separation and Purification (1 hour)
Quiz: Module 7
Learning Activities
Techniques of Separation and Purification (1 hour) ►
OChem2
General
Organic Chemistry 2 Homepage
Module 1: Carboxylic Acids
Module 1: Lesson 1: Carboxylic Acids
Module 1: Lesson 2: Synthesis of Carboxylic Acids
Module 1: Lesson 3: Carboxylic Acid Derivatives
Module 1: Lesson 4: Alpha Substitution Reactions
Module 1: Lesson 5: Carbonyl Condensation Reactions
Module 2: Aldehydes and Ketones
Module 2: Lesson 1: Properties of Aldehydes and Ketones
Module 2: Lesson 2: Synthesis of Aldehydes and Ketones
Module 2: Lesson 3: Reactivity of Aldehydes and Ketones
Module 3: Enolate Chemistry and Aldols
Module 3: Lesson 1: General Principles of the α-hydrogen on aldehydes and ketones.
Module 3: Lesson 2. Enolate Chemistry
Module 3: Lesson 3: Aldol Reactions
Module 4: Aromatic Systems and Amines
Module 4: Lesson 1: Nomenclature, Aromaticity and Aromatic Structure
Module 4: Lesson 2: Structure and Stability of Benzene
Module 4: Lesson 3: Aromaticity and the Hückel 4n + 2 Rule
Module 4: Lesson 4: Electrophilic Aromatic Substitution, Aromatic Nitration, Aromatic Slfonation
Module 4: Lesson 5: Aromatic Substitution Reactions Part II
Module 5: Nitrogen-and Phosphorus-Containing Compounds
Module 5: Lesson 1: Proteins and Peptides
Module 5: Lesson 2: Amino Acids
Module 5: Lesson 3: Phosphorus-Containing Compounds
Module 6: Spectroscopy
Module 6: Lesson 1: Principles of Molecular Spectroscopy
Module 6: Lesson 2: NMR Spectroscopy
Module 6: Lesson 3: Carbon NMR Spectroscopy
Module 6: Lesson 4: Supplemental NMR Topics
Module 6: Lesson 5: Infrared Spectroscopy
Module 6: Lesson 6: UV-Visible Spectroscopy
Module 6: Lesson 7: Mass Spectroscopy
Module 7: Separations and Purifications
Module 7: Lesson 1: Basic Concepts of Separation
Module 7: Lesson 2: Equilibrium Separations
Final Exam
Course and Self Evaluation & Certificate
Course Activities
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